Key result
Diabetes is linked to more diseased coronary vessels on angiography versus matched nondiabetic controls.
Why the study?
Is diabetes mellitus associated with a greater number of diseased vessels on coronary angiography in patients with symptoms of coronary artery disease?
Case-Control
No
Is diabetes mellitus associated with a greater number of diseased vessels on coronary angiography in patients with symptoms of coronary artery disease?
This study confirms that diabetic patients undergoing cardiac catheterization have more diffuse and severe coronary artery disease than matched nondiabetic patients.
May reflect more extensive CAD in symptomatic diabetics; confirms association in case-control data but leaves open practice implications.
Coronary artery disease is the most important complication of diabetes mellitus. The purpose of this retrospective single center study was to evaluate the association between the presence of diabetes mellitus and the findings of coronary angiography. All the patients with diabetes mellitus who underwent cardiac catheterization for symptoms of coronary artery disease at our center between March 2006 and March 2007 were identified. Nondiabetic control subjects were matched individually with diabetic patients for sex and age. Risk factors were considered according to the information provided by the patient and the laboratory parameters were retrieved from catheterization and medical records. Fewer cigarette smokers were reported among the diabetic patients, and dyslipidemia and hypertension were more frequent in this group. Diabetic patients had a significantly greater number of diseased vessels compared with nondiabetic control subjects. The present study confirms the diffuse aspect of coronary artery disease in diabetic patients.
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Mohagheghi et al. (2008) conducted a case-control in Coronary artery disease. Diabetes mellitus vs. Nondiabetic control subjects was evaluated on Number of diseased vessels on coronary angiography. Diabetic patients had a significantly greater number of diseased vessels on coronary angiography compared with age- and sex-matched nondiabetic control subjects.
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