Key result
Diabetes mellitus was associated with significantly more severe forms of coronary artery lesions, including a higher prevalence of triple vessel disease (21.2% vs 15.6%), compared to non-diabetic patients (p=0.0308).
Why the study?
Diabetes mellitus increases cardiovascular disease risk, prompting this study to evaluate the extent and complexity of cardiovascular lesions in diabetic versus non-diabetic patients.
Does diabetes mellitus increase the severity and complexity of coronary artery lesions in patients presenting with cardiac symptoms?
Case-Control (n=500)
No
Does diabetes mellitus increase the severity and complexity of coronary artery lesions in patients presenting with cardiac symptoms?
Absolute Event Rate: 21.2% vs 15.6%
p-value: p=0.0308
Diabetic patients presenting with cardiac symptoms have significantly more severe and complex coronary artery disease and worse left ventricular systolic function compared to non-diabetic patients.
Introduction: Diabetes mellitus is a complex metabolic disorder associated with an increased risk of microvascular and macrovascular disease.Type 2 diabetes mellitus is a prevalent metabolic disorder that often leads to cardiovascular diseases and diabetic cardiomyopathy, which may lead to chronic pressure overload and myocardial infarction.The present study aimed at studying the extent and complexity of cardiovascular lesions among diabetic patients and compare same with non-diabetic patients.Materials and methods: The present study was a Case-Control (Analytical and Interventional) Study conducted over 18 months (October 2016 to March 2018).Case group consisted of 250 Diabetic patients with cardiac symptoms, with or without ECG changes, who have undergone coronary angiography.And Controls group consisted of 250 Non-Diabetic patients with cardiac symptoms, with or without ECG changes, have undergone coronary angiography.Results: In the present study, among diabetics, there were 52.8% male patients and 47.2% female patients, similarly among non diabetic group, 57.2% were males and 42.8% cases were females.12.4% people were found normal, 37.6% were suffering from Single vessel disease, 28.8% people with Double vessel disease and 21.2% people with Triple vessel disease. Conclusions:According to the present study, among coronary angiography diagnosis, severe forms of coronary artery lesions were found common among diabetic patients as compared to non diabetic patients.
No takes yet. Share an insight, caveat, or question.
Bharath et al. (2019) conducted a case-control in Cardiac symptoms (n=500). Diabetes Mellitus vs. Non-diabetic patients was evaluated on Severe forms of coronary artery disease (triple vessel disease) on coronary angiography (p=0.0308). Diabetes mellitus was associated with significantly more severe forms of coronary artery lesions, including a higher prevalence of triple vessel disease (21.2% vs 15.6%), compared to non-diabetic patients (p=0.0308).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: