Key result
Indirect fluorescent antibody staining revealed extensive cross-reactions among picornaviruses, with heterologous reactions being almost as strong as homologous reactions.
Population
Green monkey kidney cells infected with picornaviruses
Design
Preclinical
Authors
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Cross-reactivity may limit IFA specificity for picornavirus typing; leaves open need for type-specific diagnostics in research and practice.
Demonstrates extensive cross-reactivity among picornaviruses using indirect fluorescent antibody staining.
Chaudhary et al. (1970) studied Picornavirus cross-reactions. Indirect method of fluorescent antibody staining was evaluated on Degree of cross-reactions within the picornavirus group. Indirect fluorescent antibody staining revealed extensive cross-reactions among picornaviruses, with heterologous reactions being almost as strong as homologous reactions.
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