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January 1, 2014Industrial Psychiatry JournalOpen Access

Catatonia versus neuroleptic malignant syndrome: the diagnostic dilemma and treatment

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Key result

Aripiprazole and bromocriptine rapidly improve symptoms in a patient with overlapping catatonia and NMS.

  • n=1

Population

A patient with catatonia and overlapping symptoms of neuroleptic malignant syndrome (NMS) from eastern India

Design

Case_report

Authors

MSManojKumar SahooSASanjay AgarwalHBHarshita Biswas

Discussion

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Overview

May aid catatonia-NMS differentiation via detailed assessment; leaves open validation in prospective studies.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 23-year-old female presenting with acute onset mutism, stupor, and generalized rigidity, posing a diagnostic dilemma between catatonia and neuroleptic malignant syndrome.
I
Intervention
Detailed history, investigation, and symptom management
O
Outcome
Patient's rapid improvement

Highlights the diagnostic dilemma between catatonia and neuroleptic malignant syndrome and the importance of detailed history and symptom management.

Limitations

  • Single case report limits generalizability
  • CPK elevation is not specific to NMS, complicating diagnosis

Cite This Study

Sahoo et al. (2014) conducted a case report in Catatonia and Neuroleptic Malignant Syndrome (n=1). Aripiprazole and bromocriptine was evaluated on Clinical improvement. Detailed history, investigation, and symptom management with aripiprazole and bromocriptine led to rapid clinical improvement in a patient presenting with overlapping symptoms of catatonia and NMS.

synapsesocial.com/papers/6aa4773c4093a38aba2bc43fhttps://doi.org/10.4103/0972-6748.151703
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Catatonia in a Possible Case of Moderate Neuroleptic Malignant Syndrome: A Case Report2025
  2. 2An Analysis of 17 Catatonic Patients Diagnosed With Neuroleptic Malignant Syndrome2000 · 43 citations
  3. 3Catatonia & Neuroleptic Malignant Syndrome2015 · 2 citations
  4. 4Catatonia and the Neuroleptic Malignant Syndrome – a Single Entity?1992 · 134 citations
  5. 5Neuroleptic Malignant Syndrome and Neuroleptic-Induced Catatonia: Differential Diagnosis and Treatment1985 · 40 citations