Key result
Right coronary dominance linked to greater CAD severity vs left or codominance.
Why the study?
Is right coronary dominance associated with increased severity of coronary artery disease in patients undergoing coronary angiography?
Cross-Sectional (n=1,654)
No
Is right coronary dominance associated with increased severity of coronary artery disease in patients undergoing coronary angiography?
Mean Difference: 6.699 (95% CI 1.193–12.205)
Absolute Event Rate: 42.3% vs 36.3%
p-value: p=0.017
Right coronary dominance is associated with more severe coronary artery disease as measured by the Gensini score in patients undergoing angiography.
Does not warrant practice change; leaves open whether dominance predicts progression or events in prospective cohorts.
OBJECTIVE: To investigate whether coronary artery dominance is associated with the severity of coronary artery disease (CAD). DESIGN: Cross-sectional study. SETTING: Single-centre. PARTICIPANTS: Between July 2015 and February 2017, 1654 patients who underwent coronary angiography (CAG) were recruited into this cross-sectional study. MEASUREMENT AND METHODS: According to coronary dominance, patients were classified into left dominance (LD), right dominance (RD) and codominance (CD) based on the CAG results. Multiple linear regression analysis was performed to test the association between severity of CAD and coronary dominance. RESULTS: The total Gensini score was significantly higher in the RD group than in the left-CD group (42.3±33.6 vs 36.3±29.8; p=0.033). After adjusting for potential confounding factors, the results of multivariate linear regression showed that RD was associated with the severity of CAD (β=6.699, 95% CI 1.193 to 12.205, p=0.017). CONCLUSIONS: The results suggest that right coronary dominance was associated with the severity of CAD.
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Yan et al. (2018) conducted a cross-sectional in Coronary artery disease (n=1,654). Right coronary dominance vs. Left dominance and codominance was evaluated on Total Gensini score (β=6.699, 95% CI 1.193 to 12.205, p=0.017). Right coronary dominance was significantly associated with increased severity of coronary artery disease, demonstrating a higher adjusted Gensini score (β=6.699) compared to left or codominance.
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