Key result
Right coronary dominance linked to ~77% higher prevalence of triple-vessel CAD.
Why the study?
The relationship between right coronary dominance and coronary angiographic characteristics in patients with or without significant CAD was unclear.
Is right coronary dominance associated with a higher prevalence of triple-vessel coronary artery disease compared to left or co-dominance in patients undergoing coronary angiography?
Cross-Sectional (n=2,225)
Is right coronary dominance associated with a higher prevalence of triple-vessel coronary artery disease compared to left or co-dominance in patients undergoing coronary angiography?
Odds Ratio: 1.768 (95% CI 1.057–2.956)
Absolute Event Rate: 36.6% vs 27.3%
p-value: p=0.030
Right coronary dominance is associated with a higher prevalence of triple-vessel coronary artery disease, suggesting it may serve as an anatomical risk factor for severe CAD.
RD may signal higher triple-vessel CAD risk; leaves open whether dominance assessment improves stratification or requires prospective validation.
This study was conducted to investigate the relationship between right coronary dominance and coronary angiographic characteristics in patients with or without significant coronary artery disease (CAD).A total of 2225 patients undergoing coronary angiography (CAG) between January 2011 and November 2014 were recruited in our study. Based on the CAG results, patients were divided into the left dominance (LD) group, right dominance (RD) group, and co-dominance (CD) group. Multinomial logistic regression was applied to analyze the relationships between coronary dominance and triple-vessel CAD.We found that patients with RD had a higher prevalence of triple-vessel CAD (36.6% vs 27.3%, P = .008) and significant stenosis in the right coronary artery (40.5% vs 29.2%, P = .001). In addition, results of multinomial logistic regression analysis showed that RD was significantly associated with the triple-vessel disease (odds ratio 1.768, 95% confidence interval 1.057-2.956, P = .030).In conclusion, RD positively correlated with triple-vessel CAD rather than LD or CD in patients. This result suggested that RD may serve as a risk factor for triple-vessel CAD and more effective measures should be taken in RD patients to prevent fatal cardiovascular events.
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Peng et al. (2018) conducted a cross-sectional in Coronary artery disease (n=2,225). Right coronary dominance vs. Left dominance or co-dominance was evaluated on Triple-vessel CAD (OR 1.768, 95% CI 1.057-2.956, p=0.030). Right coronary dominance was significantly associated with a higher prevalence of triple-vessel coronary artery disease (OR 1.768; 95% CI 1.057-2.956; P=0.030).
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