Key result
Upright exercise recovery maintains stroke volume via enhanced contractility rather than the Frank-Starling mechanism.
Why the study?
What are the hemodynamic and left ventricular function changes during recovery from upright bicycle exercise in normal persons compared to patients with coronary artery disease?
Population
86 subjects, comprising 56 normal subjects and 30 patients with documented myocardial ischemia.
Comparison
Upright bicycle exercise. vs Normal subjects vs. patients with documented…
Design
Cohort
Follow-up
7 minutes post-exercise
Authors
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Supports further investigation of contractility in exercise recovery; should not yet change practice in myocardial ischemia.
Observational (n=86)
What are the hemodynamic and left ventricular function changes during recovery from upright bicycle exercise in normal persons compared to patients with coronary artery disease?
During recovery from upright bicycle exercise, stroke volume is maintained by enhanced contractility (decreased end-systolic volume) rather than the Frank-Starling mechanism in both normal subjects and patients with myocardial ischemia.
Plotnick et al. (1986) conducted an observational in Myocardial ischemia (n=86). Upright bicycle exercise vs. Normal subjects was evaluated on Hemodynamic changes (ejection fraction, LV volumes, heart rate, blood pressure) during recovery. Upright bicycle exercise recovery demonstrated enhanced contractility maintaining stroke volume in both normal subjects and myocardial ischemia patients, rather than the Frank-Starling mechanism.
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