Key result
Peppermint aromatherapy reduces 15-minute PONV scores better than IV ondansetron after laparotomy.
Why the study?
To compare the effects of peppermint aromatherapy and intravenous ondansetron on the incidence of postoperative nausea and vomiting after laparotomy with general anesthesia.
Does peppermint aromatherapy reduce postoperative nausea and vomiting compared to intravenous ondansetron in patients undergoing laparotomy with general anesthesia?
RCT (n=36)
Double-blind
Block method
Yes
Does peppermint aromatherapy reduce postoperative nausea and vomiting compared to intravenous ondansetron in patients undergoing laparotomy with general anesthesia?
p-value: p=0.033
Peppermint aromatherapy may be more effective than intravenous ondansetron at reducing postoperative nausea and vomiting in the early minutes after laparotomy.
Peppermint aromatherapy may offer an early alternative to ondansetron for PONV after laparotomy; extends non-pharmacologic options pending confirmatory trials.
Background: Postoperative nausea and vomiting is known as Post Operative Nausea And Vomiting (PONV). Postoperative nausea and vomiting (PONV) is multifactorial and is strongly influenced by physiological factors. PONV was defined as nausea and/or vomiting occurring 24 hours postoperatively. Non-pharmacological/complementary therapies that can be used to prevent and reduce postoperative nausea and vomiting include aromatherapy. Peppermint aromatherapy can be a quick onset alternative to antiemetic therapy and is easy to administer. Objective: The purpose of this study was to determine the difference between the effects of peppermint aromatherapy and intravenous ondansetron on the incidence of postoperative nausea and vomiting (PONV) laparotomy with general anesthesia at H. Adam Malik General Hospital Medan and Network Hospital. Methods: This study is a clinical trial and uses a double-blind randomized controlled trial study design on subjects who underwent laparotomy surgery under general anesthesia at Haji Adam Malik Hospital and Network Hospital with 36 people with patients aged 18-65 years with ASA 1 and 2 physical status. who underwent laparotomy surgery under general anesthesia. Results: Statistically, there was a significant difference in PONV scores between the peppermint and ondansetron groups occurring at time T1 (15 minutes after treatment), where the p-value <0.05. Meanwhile, at times T0, T2, T3, there was no statistically significant difference in the PONV scores between the two groups, where the p-value> 0.05. Conclusion: Peppermint aromatherapy was better at reducing postoperative laparotomy with general anesthesia than standard intravenous 4 mg of ondansetron therapy, especially in the early minutes after surgery.
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Wulandari et al. (2021) conducted an RCT in Postoperative nausea and vomiting (PONV) (n=36). Peppermint aromatherapy vs. Intravenous ondansetron 4 mg was evaluated on PONV score at 15 minutes post-treatment (p=0.033). Peppermint aromatherapy significantly reduced postoperative nausea and vomiting scores at 15 minutes compared to 4 mg intravenous ondansetron (p=0.033) in patients undergoing laparotomy.
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