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March 3, 2020The Clinical Respiratory Journal

Association between risk stratification for pulmonary embolism and deep vein thrombosis of lower extremities

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Key result

High and intermediate risk PE linked to ~23% lower DVT incidence versus low risk PE.

  • P<.0001
  • n=392

Why the study?

The association of clinical risk factors, particularly deep vein thrombosis, with risk stratification for pulmonary embolism remained to be identified.

Is there an association between deep vein thrombosis characteristics and risk stratification in patients with pulmonary embolism?

Population

392 patients with pulmonary embolism

Comparison

PE risk stratification groups (high vs intermediate vs low risk by ESC criteria) and DVT characteristics

Design

Retrospective study

Authors

XWXiaohui WangUniversity of Science and Technology of ChinaLCLong‐Biao CuiSecond Affiliated Hospital of Xi'an Jiaotong UniversityYLYuliang LiuNortheast Agricultural University

Discussion

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Overview

Higher-risk PE linked to lower DVT incidence; leaves open whether asymptomatic DVT independently predicts severity and requires prospective validation.

Study Design

Type

Observational (n=392)

Structured PICO

Is there an association between deep vein thrombosis characteristics and risk stratification in patients with pulmonary embolism?

P
Population
392 patients with pulmonary embolism evaluated retrospectively to determine the association between PE risk stratification and lower extremity deep vein thrombosis.
O
Outcome
Relationship between risk stratification of PE patients (high, intermediate, and low risk based on ESC criteria) and deep vein thrombosis (DVT) of lower extremities

Main Result

Absolute Event Rate: 67.2% vs 87.8%

p-value: p=< .0001

In patients with pulmonary embolism, asymptomatic DVT is an independent risk factor for high and intermediate risk PE, despite a lower overall incidence of DVT in these higher-risk groups compared to low-risk PE.

Cite This Study

Wang et al. (2020) conducted an observational in Pulmonary embolism (n=392). High and intermediate risk pulmonary embolism vs. Low risk pulmonary embolism was evaluated on Incidence of deep vein thrombosis (DVT) (p=< .0001). High and intermediate risk pulmonary embolism was associated with a lower incidence of deep vein thrombosis compared to low risk pulmonary embolism (67.2% vs 87.8%, P<.0001).

synapsesocial.com/papers/6aa5280e4dd50f8a0764ae1ahttps://doi.org/10.1111/crj.13177
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Also Consider

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