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October 17, 2012BMC Medical ImagingOpen Access

Acute pulmonary embolism in the era of multi-detector CT: a reality in sub-Saharan Africa

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Key result

Any thromboembolic risk factor linked to ~14-fold greater risk of confirmed PE on MDCT.

  • RR 14.4
  • n=37

Population

37 patients with clinical suspicion of acute pulmonary embolism who underwent multi-detector computed…

Design

Cohort

Authors

JTJoshua TambeUniversity of BueaBMBoniface MoifoUniversité de Yaoundé IEFEmmanuel FongangUniversité de Dschang

Discussion

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Overview

Supports risk-factor–guided PE suspicion in sub-Saharan Africa; leaves open prospective validation before changing diagnostic pathways.

Study Design

Type

Observational (n=37)

Multicenter

No

Structured PICO

P
Population
37 patients with suspected acute pulmonary embolism who underwent MDCT pulmonary angiography at a single hospital in Cameroon over a two-year period.
E
Exposure
Multi-detector computed tomography (MDCT) pulmonary angiography
O
Outcome
Incidence of acute pulmonary embolism (positive MDCT angiograms)surrogate

Main Result

Relative Risk: 14.4

Absolute Event Rate: 68.8% vs 4.8%

Acute pulmonary embolism is a reality in sub-Saharan Africa, with MDCT detecting PE in 32.4% of suspected cases, strongly associated with traditional thromboembolic risk factors.

Limitations

  • Retrospective data collection
  • Small sample size
  • No other diagnostic test was performed besides MDCT angiography to further confirm or ascertain the nature of the emboli
  • retrospective data collection
  • small sample size
  • no other diagnostic test was performed besides MDCT angiography to further confirm or ascertain the nature of the emboli

Cite This Study

Tambe et al. (2012) conducted an observational in Suspected acute pulmonary embolism (n=37). Presence of at least one thromboembolic risk factor vs. Absence of thromboembolic risk factors was evaluated on Presence of acute pulmonary embolism on MDCT angiography (RR 14.4). In patients with suspected acute pulmonary embolism, the presence of at least one thromboembolic risk factor was associated with a 14.4-fold increased relative risk of confirmed PE on MDCT.

synapsesocial.com/papers/6aa5280f4dd50f8a0764ae1bhttps://doi.org/10.1186/1471-2342-12-31
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Effect of Single-Detector CT Versus MDCT on Clinical Outcomes in Patients with Suspected Acute Pulmonary Embolism and Negative Results on CT Pulmonary Angiography2005 · 43 citations
  2. 2Pulmonary Embolism: Optimization of Small Pulmonary Artery Visualization at Multi–Detector Row CT2003 · 273 citations
  3. 3CT Pulmonary Angiography: A Comparative Analysis of the Utilization Patterns in Emergency Department and Hospitalized Patients Between 1998 and 20032004 · 122 citations
  4. 4Prevalence and Significance of Nonthromboembolic Findings on Chest Computed Tomography Angiography Performed to Rule Out Pulmonary Embolism: A Multicenter Study of 1,025 Emergency Department Patients2004 · 95 citations
  5. 5Reassessment of Pulmonary Angiography for the Diagnosis of Pulmonary Embolism: Relation of Interpreter Agreement to the Order of the Involved Pulmonary Arterial Branch1999 · 204 citations