Key result
Consciousness decline precedes rigidity and fever in neuroleptic malignant syndrome, with ~80% recovering spontaneously.
Case Report (n=5)
Answers are grounded in this paper and cite their sources.
In patients with neuroleptic malignant syndrome, deterioration in consciousness may precede rigidity and fever, and spontaneous recovery can occur without specific pharmacotherapy.
Five patients with neuroleptic malignant syndrome (NMS) are described. The syndrome developed earlier and took longer to resolve in patients with schizophrenic disorders. Deterioration in the level of consciousness presented earlier than rigidity and fever in all five patients and was thus considered a major criterion. A significant proportion of the patients showed abnormalities of gaze. In four of the five patients spontaneous recovery occurred without the need for specific drugs.
No takes yet. Share an insight, caveat, or question.
Srinivasan et al. (1990) conducted a case report in Neuroleptic malignant syndrome (n=5). Neuroleptic malignant syndrome was evaluated on Clinical presentation and recovery. In five patients with neuroleptic malignant syndrome, deterioration in consciousness preceded rigidity and fever, and four of five recovered spontaneously without specific drugs.
Synapse has enriched 10 related papers. Consider them for comparative context: