Key result
Propofol shortens post-intubation hypertension duration by ~50% vs thiamylal-isoflurane during caesarean section.
Why the study?
Does propofol induction and maintenance improve maternal and neonatal outcomes compared to thiamylal-isoflurane in term parturients undergoing caesarean section?
RCT (n=74)
randomly assigned
Does propofol induction and maintenance improve maternal and neonatal outcomes compared to thiamylal-isoflurane in term parturients undergoing caesarean section?
Absolute Event Rate: 5% vs 10%
p-value: p=<0.05
Propofol for induction and maintenance of anesthesia during caesarean section is a safe alternative to thiamylal/isoflurane, offering a reduced hypertensive response to intubation.
No takes yet. Share an insight, caveat, or question.
Supports propofol as safe caesarean alternative with less post-intubation hypertension; extends RCT evidence on anaesthetic haemodynamics.
Abboud et al. (1995) conducted an RCT in caesarean section (n=74). Propofol vs. Thiamylal 3-4mg.kg-1 for induction followed by isoflurane 0.25-0.75% for maintenance was evaluated on duration of hypertension after intubation (minutes) (p=<0.05). Propofol for induction and maintenance of anaesthesia during caesarean section resulted in a shorter duration of hypertension after intubation compared to thiamylal-isoflurane (5 vs 10 minutes; P<0.05).
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: