Key result
Oblique chordal resuspension during MVR tends to improve LV systolic function versus conventional methods.
Why the study?
Does the method of chordae tendineae preservation during mitral valve replacement affect postoperative LV systolic and diastolic function in a canine model?
Population
12 dogs with normal hearts undergoing mitral valve replacement using a nondistorting isovolumic technique
Comparison
Various chordae tendineae preservation techniques vs Conventional method and control measurements
Design
Preclinical
Authors
Loading...
Does not support clinical adoption; leaves open whether oblique resuspension improves LV function in humans.
Does the method of chordae tendineae preservation during mitral valve replacement affect postoperative LV systolic and diastolic function in a canine model?
Absolute Event Rate: 4% vs 3.3%
p-value: p=0.08
In a normal canine model, the oblique method of chordal resuspension during mitral valve replacement was associated with the best LV systolic function.
Komeda et al. (1995) studied Mitral valve replacement (n=12). Oblique method of chordal resuspension vs. Conventional method (all chordae severed) was evaluated on Left ventricular systolic function (Emax) (p=0.08). The oblique method of chordal resuspension during mitral valve replacement tended to improve LV systolic function compared to the conventional method (Emax 4.0 vs 3.3 mm Hg/mL; P=0.08).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: