Key result
Fatal foot and mouth disease-induced myocarditis in a calf linked to markedly elevated serum cTn-I.
Case Report (n=2)
No
Absolute Event Rate: 26.7% vs 0.16%
Cardiac troponins and other cardiac markers are markedly elevated in a calf with myocarditis secondary to foot and mouth disease, suggesting their potential utility for rapid diagnosis.
This report disclosed changes in cardiac troponin expression during myocardial degeneration in a calf with foot and mouth disease (FMD). The case presented was a 7-day-old calf milk fed by its mother which diagnosed as having FMD (O-type) by Ministry of Agriculture and Forestry Şap (Foot and Mouth Disease) Institute. The calf suffered from myocarditis due to suckling FMD infected dam. Blood sample was taken from the jugular vein of calf. Serum cTn-T, cTn-I, CK-MB, LDH, AST and ALT levels were measured using commercial kits. cTn-T, cTn-I, CK-MB, LDH, AST and ALT levels were determined as 1.00 ng/mL, 26.68 ng/mL, 262 U/L, 4503 U/L, 56.6 U/L, 55.3 U/L, respectively and these values were higher than those of healthy calf. It is thought that the use of cardiac troponins (cTn-I, cTn-T) for the diagnosis of the disease will give accurate and rapid results.
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Ayvazoğlu et al. (2022) conducted a case report in Foot and mouth disease (FMD) with myocarditis (n=2). Foot and mouth disease (FMD) infection vs. Healthy calf was evaluated on Serum cTn-I level (ng/mL). A 7-day-old calf that died from foot and mouth disease-induced myocarditis had markedly elevated serum cTn-I (26.7 ng/mL) and cTn-T (1.00 ng/mL) compared to a healthy calf.
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