Key result
Antagonizing pro-inflammatory cytokines emerges as a potential novel therapeutic target for CHF.
Population
Patients with heart failure and experimental models
Design
Review
Authors
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Hypothesis-generating for cytokine antagonism in heart failure; prospective trials required before any clinical consideration.
This review highlights the role of pro-inflammatory cytokines in heart failure pathogenesis and their potential as therapeutic targets.
Dibbs et al. (1999) conducted a review in Heart failure. Antagonizing cytokines was evaluated. Pro-inflammatory cytokines may play a role in the pathogenesis of congestive heart failure, and antagonizing them represents a potential novel therapeutic target.
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