Key result
Intrathecal morphine lowers overall morphine consumption and improves satisfaction versus sham in gynecologic malignancy surgery.
Why the study?
Surgery for gynecologic malignancies often requires a midline laparotomy incision incurring high pain scores, requiring tailored multimodal analgesia.
Does intrathecal morphine reduce overall morphine consumption and improve satisfaction in adult patients undergoing surgery for gynecologic malignancies?
Population
68 adult patients aged 19 to 70 with ASA status less than 3 undergoing gynecologic malignancy surgery
Comparison
Intrathecal morphine vs sham procedure
Design
Randomized trial
Authors
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May support intrathecal morphine in gynecologic oncology surgery; hypothesis-generating from Level 5 evidence and needs RCT confirmation.
RCT (n=68)
Does intrathecal morphine reduce overall morphine consumption and improve satisfaction in adult patients undergoing surgery for gynecologic malignancies?
Intrathecal morphine reduces overall morphine consumption and improves patient satisfaction in gynecologic oncology surgery.
Naveen Nathan (2023) conducted an RCT in Gynecologic malignancies requiring surgery (n=68). Intrathecal morphine vs. Sham procedure was evaluated on Overall morphine consumption and satisfaction. Intrathecal morphine resulted in lower overall morphine consumption and better satisfaction compared to a sham procedure in patients undergoing surgery for gynecologic malignancies.
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