Key result
Indobufen plus compression stockings cuts recurrent DVT by ~95% versus control.
Why the study?
Does prophylaxis with indobufen, graduated elastic compression stockings, or their combination prevent recurrent deep venous thrombosis in patients after an episode of DVT?
Population
224 patients after an episode of deep venous thrombosis (DVT)
Comparison
Indobufen, graduated elastic compression… vs Control group (no specific prophylaxis mentioned)
Design
RCT, Randomized into four groups
Follow-up
3 years
Authors
Loading...
Supports combined indobufen and compression stockings for post-DVT secondary prevention; confirms substantial recurrent DVT reduction in this RCT.
RCT (n=224)
randomized
Does prophylaxis with indobufen, graduated elastic compression stockings, or their combination prevent recurrent deep venous thrombosis in patients after an episode of DVT?
Absolute Event Rate: 2.08% vs 46%
Prophylaxis with indobufen, graduated compression stockings, or their combination significantly reduces the incidence of recurrent DVT over 3 years compared to control.
Belcaro et al. (1993) conducted an RCT in deep venous thrombosis (DVT) (n=224). Indobufen and graduated elastic compression stockings vs. Control was evaluated on recurrent DVT (RDVT). Prophylaxis with a combination of indobufen and graduated elastic compression stockings significantly reduced the incidence of recurrent DVT compared to control (2.08% vs 46%).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: