Key result
Ultraviolet light triggers mammalian platelet aggregation, enhanced by fibrinogen and inhibited by EDTA.
Why the study?
Does exposure to ultraviolet light induce aggregation in mammalian blood platelets?
Population
Mammalian blood platelets
Design
Preclinical
Authors
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UV light offers a removable stimulus for in vitro platelet studies; leaves open clinical translation from this Level 5 animal model.
Does exposure to ultraviolet light induce aggregation in mammalian blood platelets?
Ultraviolet light serves as a novel stimulus for platelet aggregation, enabling the study of aggregation after the stimulus is removed.
Dickson et al. (1971) studied this question. Ultraviolet light was evaluated on Platelet aggregation. Exposure to ultraviolet light (253.7 nanometers) causes mammalian blood platelets to aggregate, an effect enhanced by extracellular fibrinogen and inhibited by EDTA.
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