Key result
Complex robotic-assisted mitral valve repair achieves similar four-week regurgitation rates as non-complex cases.
Why the study?
To evaluate the feasibility, safety, and quality of robotic-assisted mitral valve repair in complex versus non-complex cases during the early phase of a programme.
Does robotic-assisted mitral valve repair provide safe and effective outcomes in complex cases compared to non-complex cases during the early phase of a program?
Cohort (n=100)
Does robotic-assisted mitral valve repair provide safe and effective outcomes in complex cases compared to non-complex cases during the early phase of a program?
Absolute Event Rate: 95.2% vs 98.7%
p-value: p=0.47
Complex mitral valve repair can be safely and effectively performed with robotic assistance during the early phase of a program, yielding similar short-term clinical outcomes to non-complex cases despite longer operative times.
Supports robotic complex mitral repair feasibility in early programs; leaves open durability and generalizability in larger trials.
OBJECTIVES: To evaluate the feasibility, safety and quality of robotic-assisted mitral valve repair in complex versus non-complex cases during the early phase of a programme. METHODS: Since the programme launch in September 2021 until February 2024, 100 patients underwent robotic-assisted mitral valve repair. Of them, 21 patients had complex repairs, while 79 had non-complex repairs. The median age was 58 years for complex cases and 61 years for non-complex cases (P = 0.36). RESULTS: Bileaflet prolapse was significantly more prevalent in the complex group (52.4% vs 12.7%, P < 0.001). Neochord placement (61.9% vs 13.9%, P < 0.001) and commissuroplasty (28.6% vs 5.1%, P = 0.005) were more frequent in the complex group. The complex group had longer cardiopulmonary bypass times (161 vs 141 min, P < 0.001), aortic cross-clamp times (123 vs 102 min, P < 0.001) and leaflet repair times (43 vs 24 min, P < 0.001). Second pump runs were required more often for complex cases (23.8% vs 3.8%, P = 0.01). All patients left the operating room with residual mitral regurgitation of mild or less. Fewer complex patients were extubated in the operating room (42.9% vs 70.9%, P = 0.02), yet hospital stay was similar (4 vs 4 days, P = 0.56). There were no significant differences in postoperative adverse events. There were no differences in mitral regurgitation of mild or less 4 weeks post-surgery (95.2% vs 98.7%, P = 0.47). CONCLUSIONS: Complex mitral valve repair can be safely and effectively performed with robotic assistance, even in the early phase of a programme. Despite longer operative and ventilation times in the complex group, hospital stay and postoperative adverse events remained similar.
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Kobayashi et al. (2024) conducted a cohort in Mitral valve disease (n=100). Complex robotic-assisted mitral valve repair vs. Non-complex robotic-assisted mitral valve repair was evaluated on Mitral regurgitation of mild or less 4 weeks post-surgery (p=0.47). Complex robotic-assisted mitral valve repair achieved similar rates of mild or less mitral regurgitation at 4 weeks compared to non-complex repair (95.2% vs 98.7%, P=0.47).
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