Key result
Elevated 12-hour postoperative BNP linked to greater need for mechanical ventilation.
Why the study?
Does perioperative B-type natriuretic peptide (BNP) predict postoperative outcomes in patients undergoing off-pump coronary artery bypass grafting?
Cohort (n=145)
No
Does perioperative B-type natriuretic peptide (BNP) predict postoperative outcomes in patients undergoing off-pump coronary artery bypass grafting?
Effect estimate: Wald=3.956 (95% CI 1.023-20.476)
p-value: p=<0.049
Elevated 12-hour postoperative BNP is significantly associated with prolonged mechanical ventilation and longer hospital stay in patients undergoing off-pump CABG.
No takes yet. Share an insight, caveat, or question.
May identify high-risk off-pump CABG patients; leaves open whether BNP-guided strategies reduce ventilation needs.
Zhi Gang Guo (2014) conducted a cohort in Off-pump coronary artery bypass grafting (n=145). 12-hour postoperative B-type natriuretic peptide (BNP) vs. Lower BNP levels was evaluated on Requirement of mechanical ventilation (Wald=3.956, 95% CI 1.023-20.476, p=<0.049). Elevated 12-hour postoperative B-type natriuretic peptide levels were significantly associated with an increased requirement for mechanical ventilation.
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