Key result
Long-term minoxidil therapy significantly reduced blood pressure from 205/120 to 150/80 mm Hg (p < 0.001) in patients with refractory hypertension and advanced renal failure.
Why the study?
Does minoxidil reduce blood pressure in patients with refractory hypertension and severe renal failure?
Population
58 patients with refractory hypertension and severe renal failure (most on maintenance hemodialysis)
Design
Case_series
Authors
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May support minoxidil trial in refractory hypertension with renal failure; leaves open confirmation in controlled studies.
Observational (n=58)
Does minoxidil reduce blood pressure in patients with refractory hypertension and severe renal failure?
Effect estimate: Decreased from 205/120 to 150/80 mm Hg
p-value: p=<0.001
Long-term minoxidil therapy significantly reduces blood pressure in patients with refractory hypertension and advanced renal failure, with manageable side effects.
Javier et al. (1980) conducted an observational in Refractory hypertension and severe renal failure (n=58). Minoxidil was evaluated on Blood pressure (Decreased from 205/120 to 150/80 mm Hg, p=<0.001). Long-term minoxidil therapy significantly reduced blood pressure from 205/120 to 150/80 mm Hg (p < 0.001) in patients with refractory hypertension and advanced renal failure.
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