Key result
Ergonovine provocation reveals coronary artery spasm in ~36% of patients with unexplained syncope.
Why the study?
Does the ergonovine provocation test identify coronary spasm as a cause in patients with unexplained transient loss of consciousness?
Observational (n=32)
No
Does the ergonovine provocation test identify coronary spasm as a cause in patients with unexplained transient loss of consciousness?
Coronary spasm may be an underrecognized cause of unexplained transient loss of consciousness even without preceding chest pain, and ergonovine provocation testing can be useful for diagnosis.
May support spasm evaluation in unexplained syncope; hypothesis-generating and requires prospective validation before practice change.
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Tanabe et al. (1991) conducted an observational in Transient loss of consciousness (syncope) (n=32). Ergonovine provocation test was evaluated on Induction of coronary artery spasm in patients with unexplained syncope. Coronary artery spasm was identified as the cause of transient loss of consciousness in 13% of consecutive emergency room patients, and was induced by ergonovine provocation in 36% of those with unexplained syncope.
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