Key result
Amphiphilic pMPC coating for polymeric heart valves yields superior anti-inflammatory and anti-calcification properties versus hydrogels.
Amphiphilic pMPC coatings demonstrate promising anti-inflammatory and anti-calcification properties, suggesting potential for improving the biocompatibility of polymeric heart valves.
Promising for polymeric valve development; leaves open clinical translation pending human trials.
subcutaneous implantation studies demonstrated that the amphiphilic pMPC coating showed superior anti-inflammatory and anti-calcification properties. Considering the remarkable stability and optimal biocompatibility, the amphiphilic pMPC coating constructed by surface-initiated polymerization holds promising potential for modifying PHVs.
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Chen et al. (2024) studied this question. Amphiphilic pMPC coating for polymeric heart valves demonstrated superior anti-inflammatory and anti-calcification properties alongside remarkable stability and optimal biocompatibility.
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