Key result
APO C-III*D deficiency allele linked to lower APO C-III, cholesterol, and triglycerides in Mayan population.
Observational
The identification of an APO C-III deficiency allele in the Mayan population associated with lower cholesterol and triglycerides supports the role of APO C-III in lipoprotein metabolism.
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Supports APO C-III role in lipid metabolism among Mayans; leaves open effects on cardiovascular outcomes.
Ferrell et al. (1990) reported an observational. APO C-III*D allele was evaluated on Total plasma APO C-III, cholesterol, and triglyceride levels. The APO C-III*D deficiency allele (gene frequency 0.59) in the Mayan population was associated with lower levels of plasma APO C-III, cholesterol, and triglycerides.
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