Key result
Prolonged blood passage time correlates with lower FMD, linking impaired blood rheology to endothelial dysfunction.
Why the study?
Is impaired blood rheology associated with endothelial dysfunction in patients with coronary risk factors?
Population
95 patients with coronary risk factors and 37 healthy controls (total n=132)
Design
Cross-sectional
Authors
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May support blood passage time as endothelial marker in at-risk patients; leaves open incremental prognostic value and need for prospective validation.
Cross-Sectional (n=132)
Is impaired blood rheology associated with endothelial dysfunction in patients with coronary risk factors?
Effect estimate: r = -0.331
p-value: p=<0.01
Blood passage time measured by the microchannel method is closely associated with flow-mediated vasodilatation in patients with coronary risk factors, suggesting its utility as a marker of endothelial function and atherosclerosis.
Yagi et al. (2016) conducted a cross-sectional in Coronary risk factors (n=132). Blood passage time (BPT) vs. Healthy controls was evaluated on Correlation between blood passage time (BPT) and flow-mediated vasodilatation (FMD) (r = -0.331, p=<0.01). In patients with coronary risk factors, blood passage time was significantly correlated with flow-mediated vasodilatation (r = -0.331, p<0.01), linking impaired blood rheology to endothelial dysfunction.
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