Key result
Risperidone use linked to neuroleptic malignant syndrome resolving within 48 hours of drug discontinuation.
Case Report (n=1)
No
Reports a case of neuroleptic malignant syndrome successfully managed with a week of hospital treatment.
Neuroleptic malignant syndrome (NMS) is a life-threatening emergency that is often seen as a complication of antipsychotic agents. It is characterized by a tetrad of motor, behavioral, autonomic, and laboratory abnormalities. We report a case of a 34-year-old man with a history of newly diagnosed Type 2 diabetes mellitus, mental retardation, and behavioral abnormalities who developed NMS after starting on antipsychotic agents. He presented with high temperature, muscle rigidity, tachycardia, and elevated blood pressure. After a week of hospital treatment in the general ward of a secondary care unit, he was discharged in a hemodynamically and mentally stable state.
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Rajamani et al. (2016) conducted a case report in Neuroleptic malignant syndrome (n=1). Risperidone was evaluated on Clinical recovery from neuroleptic malignant syndrome. A 34-year-old man developed neuroleptic malignant syndrome one week after starting risperidone and fully recovered within 48 hours of drug discontinuation and supportive therapy.
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