What does this research mean for the field?

Increased arterial stiffness measured by Osler's manoeuvre is not associated with elevated blood pressure levels across age groups. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

January 1, 1989Journal of Hypertension

Do subjects with stiff arteries have high blood pressure?

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Arterial stiffness (n=250). Intervention: Arterial stiffness (positive Osler's manoeuvre) vs. No arterial stiffness (negative Osler's manoeuvre). Primary outcome: Blood pressure levels.

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Key result

Arterial stiffness measured by Osler's manoeuvre is not associated with raised blood pressure.

n=250

Why the study?

Does arterial stiffness as measured by Osler's manoeuvre lead to spuriously high blood pressure measurements in hospital inpatients?

Population

250 hospital inpatients

Comparison

Positive Osler's manoeuvre vs Negative Osler's manoeuvre

Design

Cross-sectional

Authors

JCJohn P. CoxEmory University RERuth EnglandVoestalpine (Brazil)TCTony CoxEuropean Bioinformatics Institute

Discussion

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Implication

Osler's manoeuvre does not indicate spurious BP elevation in inpatients; leaves open validation against gold-standard stiffness measures in prospective cohorts.

Study Design

Type

Cross-Sectional (n=250)

Structured PICO

Does arterial stiffness as measured by Osler's manoeuvre lead to spuriously high blood pressure measurements in hospital inpatients?

Population

250 hospital inpatients assessed for arterial stiffness using Osler's manoeuvre to evaluate its relationship with blood pressure levels.

Exposure

Positive Osler's manoeuvre (indicating arterial stiffness)

Comparator

Negative Osler's manoeuvre (patients of similar age without arterial stiffness)

Outcome

Blood pressure levelssurrogate

Increased arterial stiffness assessed by Osler's manoeuvre is not associated with spuriously elevated blood pressure readings in older patients.

Cite This Study

Cox et al. (1989) conducted a cross-sectional in Arterial stiffness (n=250). Arterial stiffness (positive Osler's manoeuvre) vs. No arterial stiffness (negative Osler's manoeuvre) was evaluated on Blood pressure levels. Arterial stiffness measured by Osler's manoeuvre was not associated with raised blood pressure levels across age groups.

synapsesocial.com/papers/6aa7c138b05f134000da0ae6 https://doi.org/10.1097/00004872-198900076-00037

Topics

Hypertension management

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Implication

Osler's manoeuvre does not indicate spurious BP elevation in inpatients; leaves open validation against gold-standard stiffness measures in prospective cohorts.

Do subjects with stiff arteries have high blood pressure?

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Topics

Do subjects with stiff arteries have high blood pressure?

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider