Key result
Abnormal second-trimester peripheral pulse wave augmentation predicts preeclampsia with ~91% sensitivity.
Why the study?
This study was conducted to define the relation between arterial stiffness and perinatal outcome, exploring maternal pulse wave augmentation index and adverse perinatal outcomes.
Does abnormal peripheral pulse wave augmentation in the second trimester predict preeclampsia in women with singleton pregnancies?
Population
Women with singleton pregnancy in the second trimester at a tertiary care center
Comparison
Peripheral pulse waveform augmentation index and mean arterial pressure measurements
Authors
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May support second-trimester vascular screening for preeclampsia; leaves open prospective validation before changing practice.
Observational
No
Does abnormal peripheral pulse wave augmentation in the second trimester predict preeclampsia in women with singleton pregnancies?
Effect estimate: Sensitivity 91.23%, Specificity 99.06%
p-value: p=<0.05
Abnormal peripheral pulse wave augmentation combined with mean arterial pressure in the second trimester is a highly sensitive and specific tool for predicting early-onset preeclampsia.
S et al. (2022) conducted an observational in Preeclampsia. Abnormal peripheral pulse wave augmentation and mean arterial pressure was evaluated on Prediction of preeclampsia (Sensitivity 91.23%, Specificity 99.06%, p=<0.05). Abnormal peripheral pulse wave augmentation in the second trimester predicted preeclampsia with a sensitivity of 91.23% and specificity of 99.06% (P<0.05).
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