What does this research mean for the field?

Recording high right precordial leads during an ajmaline provocation test can reveal diagnostic type 1 Brugada electrocardiographic patterns that are absent in standard lead positions. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 2006Journal of Cardiovascular Pharmacology and Therapeutics

Recording of High V1-V3 Precordial Leads May Be Essential to the Diagnosis of Brugada Syndrome During the Ajmaline Test

Q: What is the clinical evidence from this study?

Study design: Case Report. Population: Brugada syndrome (n=1). Intervention: High V1-V3 precordial leads recording during ajmaline test vs. Conventional precordial leads. Primary outcome: Type 1 pattern of the Brugada syndrome.

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Key result

High right precordial leads during ajmaline testing unmask Brugada syndrome missed by conventional leads.

Why the study?

Does recording high V1-V3 precordial leads during the ajmaline test improve the diagnosis of Brugada syndrome in patients with syncope of unknown origin?

Population

A patient with syncopal episodes of unknown origin in whom the conventional electrocardiographic result was…

Comparison

Intravenous ajmaline with recording of high… vs Intravenous ajmaline with precordial leads…

Design

Case_report

Authors

RTRodrigo TeijeiroUniversidad Columbia del Paraguay HGHugo GarroSocietà Italiana di Cardiologia RARafael S. AcunzoHospital Ramos Mejía

Discussion

Member takes

Implication

May support high-lead recording in ajmaline testing for unexplained syncope; leaves open need for prospective validation before routine adoption.

Study Design

Type

Case Report (n=1)

Structured PICO

Does recording high V1-V3 precordial leads during the ajmaline test improve the diagnosis of Brugada syndrome in patients with syncope of unknown origin?

Population

1 patient with syncopal episodes of unknown origin undergoing an ajmaline test for suspected Brugada syndrome.

Intervention

Intravenous ajmaline (50 mg) with recording of high right precordial leads (V1-V3 recorded 2 intercostal spaces above the conventional site)

Comparator

Intravenous ajmaline (50 mg) with precordial leads obtained at their usual level

Outcome

Elicitation of the type 1 pattern of Brugada syndrome (coved-type repolarization)surrogate

Recording high precordial leads during the ajmaline test may be essential to unveil the type 1 Brugada pattern in suspected patients.

Cite This Study

Teijeiro et al. (2006) conducted a case report in Brugada syndrome (n=1). High V1-V3 precordial leads recording during ajmaline test vs. Conventional precordial leads was evaluated on Type 1 pattern of the Brugada syndrome. Recording high right precordial leads during an intravenous ajmaline test revealed a clear-cut coved-type repolarization indicative of Brugada syndrome that was absent in conventional leads.

synapsesocial.com/papers/6aa8830c06cac289bb0c4885 https://doi.org/10.1177/1074248406288760

Topics

Cardiac device therapy

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Implication

May support high-lead recording in ajmaline testing for unexplained syncope; leaves open need for prospective validation before routine adoption.

Recording of High V1-V3 Precordial Leads May Be Essential to the Diagnosis of Brugada Syndrome During the Ajmaline Test

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Topics

Recording of High V1-V3 Precordial Leads May Be Essential to the Diagnosis of Brugada Syndrome During the Ajmaline Test

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

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