Key result
Standard ICD-EG analysis distinguishes LV impulse sites two centimeters apart with ~96% sensitivity.
Why the study?
Can standard ICD electrogram analysis regionalize left ventricular sites of impulse formation and distinguish between paced sites?
Population
24 patients undergoing left ventricular electro-anatomic mapping and pacing
Design
Cohort, Blinded visual analysis for spatial resolution
Authors
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ICD-EG analysis from RV apex may aid LV impulse regionalization; leaves open whether resolution supports routine VT ablation guidance.
Observational (n=24)
Blinded visual analysis
Can standard ICD electrogram analysis regionalize left ventricular sites of impulse formation and distinguish between paced sites?
Absolute Event Rate: 96% vs 84%
p-value: p=<0.001
Standard ICD electrogram analysis can accurately regionalize left ventricular sites of impulse formation and distinguish between sites ≥2 cm apart.
Almendral et al. (2011) conducted an observational in Ventricular tachycardia (n=24). Standard ICD-EG analysis vs. Distance < 2 cm between sites was evaluated on Sensitivity for recognition of paced sites as different by electrogram inspection (p=<0.001). Standard ICD-EG analysis accurately distinguished between two left ventricular sites of impulse formation, with sensitivity increasing from 84% to 96% if sites were ≥2 cm apart (P<0.001).
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