Key result
Mean arterial pressure, stroke volume, and uterine artery pulsatility index at 11-14 weeks predict preeclampsia.
Why the study?
Do maternal cardiac function and uterine artery Doppler at 11-14 weeks predict preeclampsia in nulliparous women?
Population
534 nulliparous women with singleton pregnancies presenting consecutively to a maternity unit of a teaching…
Design
Cohort
Authors
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May support early preeclampsia risk stratification in nulliparous women; leaves open prospective validation before clinical adoption.
Observational (n=534)
No
Do maternal cardiac function and uterine artery Doppler at 11-14 weeks predict preeclampsia in nulliparous women?
Maternal cardiac function and uterine artery Doppler parameters assessed at 11-14 weeks' gestation can independently predict the subsequent development of preeclampsia.
Khaw et al. (2008) conducted an observational in Preeclampsia (n=534). Maternal cardiac function and uterine artery Doppler vs. Normal outcome was evaluated on Preeclampsia. Mean arterial pressure, stroke volume, and uterine artery pulsatility index at 11 to 14 weeks' gestation were identified as independent predictors of preeclampsia.
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