Key result
Heart transplant after complex therapies enables 10-day discharge in a patient with severe DCM.
Why the study?
This case study focuses on the multiple therapeutic strategies required to manage a patient with severe dilated cardiomyopathy.
Case Report (n=1)
This case demonstrates the feasibility of utilizing a complex sequence of advanced mechanical and surgical therapies as a bridge to heart transplantation in a patient with severe, deteriorating dilated cardiomyopathy.
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Supports feasibility of sequential advanced therapies including total artificial heart in refractory cardiomyopathy; leaves open generalizability and optimal sequencing.
Pettillo et al. (2026) conducted a case report in Severe primary dilated cardiomyopathy (n=1). Sequential cardiac therapies (CRT-D, S-ICD, Mitraclip, Impella, CARMAT TAH, heart transplant) was evaluated on Clinical course and survival. A 47-year-old man with severe dilated cardiomyopathy survived a complex sequence of therapies culminating in a heart transplant, and was discharged 10 days after surgery.
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