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January 1, 1996Japanese Circulation Journal-english EditionOpen Access

Advantages and Disadvantages of Dobutamine Stress Echocardiography Compared With Treadmill Exercise Electrocardiography in Detecting Ischemia

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Key result

DSE outperforms treadmill testing in detecting CAD, yielding ~82% accuracy.

  • P<0.01
  • n=96

Why the study?

Does dobutamine stress echocardiography improve the detection of ischemia compared to treadmill exercise electrocardiography in patients presenting for coronary angiography?

Population

96 patients presenting for coronary angiography, mean age 58.8 +/- 9.0 years.

Comparison

Dobutamine stress echocardiography with… vs Symptom-limited treadmill exercise…

Design

Cross-sectional

Authors

MIMasatsugu IwaseFujita Health UniversityMFMasako FukuiHTHiromi Tamagaki

Discussion

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Implication

May support dobutamine stress echocardiography over treadmill testing for CAD detection; leaves open whether it improves outcomes or warrants practice change.

Study Design

Type

Cross-Sectional (n=96)

Structured PICO

Does dobutamine stress echocardiography improve the detection of ischemia compared to treadmill exercise electrocardiography in patients presenting for coronary angiography?

P
Population
96 patients (mean age 58.8 years) presenting for coronary angiography who underwent both dobutamine stress echocardiography and treadmill exercise testing.
E
Exposure
Dobutamine stress echocardiography (DSE) with incremental dobutamine infusion (5-40 micrograms/kg per min administered in 5 min steps).
C
Comparator
Symptom-limited treadmill exercise electrocardiographic testing (TMT).
O
Outcome
Sensitivity, specificity, and accuracy of detecting ischemia (coronary artery disease).surrogate

Main Result

Absolute Event Rate: 82% vs 63%

p-value: p=<0.01

Dobutamine stress echocardiography is more sensitive, specific, and accurate than treadmill exercise ECG for detecting coronary artery disease, though it takes significantly longer to perform.

Limitations

  • DSE takes longer to perform than TMT and thus may be less suitable for routine clinical use.

Cite This Study

Iwase et al. (1996) conducted a cross-sectional in Coronary artery disease (n=96). Dobutamine stress echocardiography (DSE) vs. Treadmill exercise electrocardiographic testing (TMT) was evaluated on Accuracy in detecting ischemia (p=<0.01). Dobutamine stress echocardiography was more accurate than treadmill exercise testing in detecting coronary artery disease (82% vs 63%, p<0.01).

synapsesocial.com/papers/6aa91da0231e8f09c2acb7d4https://doi.org/10.1253/jcj.60.954

Topics

Echocardiography
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exercise echocardiography versus 201Tl single-photon emission computed tomography in evaluation of coronary artery disease. Analysis of 292 patients.1992 · 320 citations
  2. 2Comparison of exercise electrocardiography and dobutamine echocardiography1992 · 14 citations
  3. 3The physiologic basis of dobutamine as compared with dipyridamole stress interventions in the assessment of critical coronary stenosis.1987 · 244 citations
  4. 46.ウイルス性心筋炎と心筋症1979 · 54 citations