Key result
IBD is linked to higher pulse wave velocity, inflammatory markers, and insulin resistance versus controls.
Why the study?
Is inflammatory bowel disease associated with increased pulse wave velocity and insulin resistance independent of conventional cardiovascular risk factors?
Population
102 patients with inflammatory bowel disease without cardiovascular risk factors, evaluated in active and…
Design
Cohort
Authors
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May warrant closer CV surveillance in IBD; hypothesis-generating for inflammation-driven vascular risk beyond traditional factors.
Case-Control (n=176)
Is inflammatory bowel disease associated with increased pulse wave velocity and insulin resistance independent of conventional cardiovascular risk factors?
p-value: p=<0.05
Inflammatory bowel disease is associated with increased arterial stiffness and inflammation-related factors independent of conventional cardiovascular risk factors.
Korkmaz et al. (2014) conducted a case-control in Inflammatory bowel disease (n=176). Inflammatory bowel disease vs. Matched controls without inflammatory bowel disease was evaluated on 24 h, day and night pulse wave velocity (PWV) values, erythrocyte sedimentation rate, C-reactive protein, insulin, HOMA-IR, and homocysteine (p=<0.05). Inflammatory bowel disease was associated with higher pulse wave velocity, inflammatory markers, and insulin resistance compared to controls (P<0.05).
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