Key result
IBD is linked to increased arterial stiffness surpassing well-controlled hypertension in older patients.
Why the study?
Chronic inflammatory diseases are related to earlier onset of atherosclerosis, but arterial stiffness in inflammatory bowel disease patients without hypertension or diabetes compared to well-controlled hypertension patients was unclear.
Does inflammatory bowel disease increase arterial stiffness similarly to well-controlled hypertension?
Population
89 inflammatory bowel disease patients without hypertension or diabetes and 73 age-matched well-controlled hypertension patients
Comparison
Inflammatory bowel disease patients vs well-controlled arterial hypertension patients
Design
Observational cross-sectional study
Authors
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Arterial stiffness may warrant monitoring in IBD; leaves open its independence from hypertension as a vascular risk marker.
Observational (n=162)
Does inflammatory bowel disease increase arterial stiffness similarly to well-controlled hypertension?
Inflammatory bowel disease is associated with increased arterial stiffness comparable to or exceeding that of well-controlled hypertension, suggesting IBD duration is a risk factor for subclinical organ damage.
Prijić et al. (2018) conducted an observational in Inflammatory bowel disease (n=162). Inflammatory bowel disease vs. Well-controlled arterial hypertension was evaluated on Pulse wave velocity (PWV) and augmentation index (AIx). Inflammatory bowel disease was associated with increased arterial stiffness, with pulse wave velocity values surpassing those of well-controlled hypertensive patients in older age quartiles.
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