Key result
Pericardial covered stents successfully treat ~100% of refractory coronary perforations despite subsequent restenosis and thrombosis.
Why the study?
Iatrogenic coronary perforation is a rare life-threatening complication of PCI, and current covered stents have limited deliverability in difficult anatomy, necessitating evaluation of pericardial covered stents.
Does a pericardial covered stent safely and effectively treat coronary perforations during PCI?
Observational (n=9)
Yes
Does a pericardial covered stent safely and effectively treat coronary perforations during PCI?
Pericardial covered stents provide a highly deliverable and effective treatment option for iatrogenic coronary perforations when balloon inflation is insufficient, though risk of restenosis and thrombosis remains.
Should not yet change practice for refractory perforations; leaves open the role of pericardial covered stents pending prospective data.
OBJECTIVES: To evaluate initial and long term results of coronary perforation treatment with pericardial covered stent. BACKGROUND: Iatrogenic coronary perforation is a rare life threatening complication of percutaneous coronary interventions (PCI) occurring in 0.1-0.8% of cases. Covered stents are the mainstay of therapy for coronary perforation. However, polytetrafluoroethylene covered stents are bulky with limited flexibility and thus may not be easy to deliver in difficult anatomy. Therefore, they are reserved to perforations in proximal or mid straight segments where their delivery is relatively easy. The pericardial covered stent is a highly deliverable fully covered stent that may be used to treat coronary perforations. Only a single case has been reported of the use of this stent in its previous version for the treatment of coronary perforation. METHODS: The electronic databases of four tertiary medical centers were retrospectively reviewed for cases of coronary perforations in which PCS was used. During a five years period, between 2008 and 2013, 18,364 patients underwent PCI in these centers. Nine cases of perforations for which balloon dilatation was not sufficient and pericardial covered stent was used were recorded. RESULTS: All nine cases were successfully treated with pericardial covered stent. Six of the patients underwent repeated angiography at 2-15 months, and in two of them instent restenosis that warranted repeated angioplasty was observed. One of them was catheterized for NSTEMI 3 months after the covered stent implantation, and stent thrombosis was demonstrated. CONCLUSIONS: Pericardial covered stents offer a safe and effective therapy for coronary perforation when balloon inflation and reversal of anticoagulation are insufficient.
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Chen et al. (2015) conducted an observational in Coronary perforation during PCI (n=9). Pericardial covered stent was evaluated on Successful treatment of coronary perforation. Pericardial covered stents successfully treated 100% (9 of 9) of coronary perforations refractory to balloon dilatation, with 2 cases of restenosis and 1 stent thrombosis during follow-up.
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