Key result
Clinical SYNTAX score outperforms standard SYNTAX score in predicting mortality after left main PCI.
Why the study?
Risk scoring systems for pre-PCI risk stratification in patients undergoing PCI for unprotected left main coronary artery disease require assessment for prognostic value.
Does the Clinical SYNTAX score provide better prognostic value than the anatomical SYNTAX score for outcomes in patients undergoing PCI for unprotected left main coronary artery disease?
Population
198 consecutive patients with unprotected LM disease undergoing PCI
Comparison
Clinical SYNTAX score and EuroSCORE vs SYNTAX score
Design
Observational cohort study
Follow-up
1 year
Authors
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May aid risk stratification in left main PCI; leaves open whether Clinical SYNTAX score should guide decisions pending validation.
Observational (n=198)
Does the Clinical SYNTAX score provide better prognostic value than the anatomical SYNTAX score for outcomes in patients undergoing PCI for unprotected left main coronary artery disease?
p-value: p=<0.01
The Clinical SYNTAX score and EuroSCORE are independent predictors of 30-day and 1-year outcomes in patients undergoing left main PCI, with CSS showing superior discriminatory ability compared to the anatomical SYNTAX score alone.
Jou et al. (2012) conducted an observational in unprotected left main coronary artery disease (n=198). Clinical SYNTAX score (CSS) vs. SYNTAX score was evaluated on 30-day and 1-year all-cause death and major adverse cardiovascular events (MACE) (p=<0.01). The Clinical SYNTAX score demonstrated superior predictive accuracy for 30-day and 1-year all-cause death compared to the SYNTAX score (P<0.01) in patients undergoing left main PCI.
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