June 1, 1987Journal of Hypertension
Determinants of Rise in Blood Pressure in Normotensive Children
Key result
Large 7-year pediatric systolic BP increases link to greater weight gain and initial BP drops.
- n=117
Why the study?
Determinants of rise in blood pressure in initially normotensive children over time were not well characterized.
What are the determinants of a large rise in systolic blood pressure over 7 years in initially normotensive children?
Comparison
Children with large increase in SBP vs children with small increase in SBP
Design
Case-control study
Follow-up
7 years
Authors
Discussion
Loading...
Member takes
Implication
May flag future SBP rise via weight gain and early BP fall in children; hypothesis-generating, needs prospective validation before any monitoring change.
Study Design
Type
Case-Control (n=117)
Structured PICO
What are the determinants of a large rise in systolic blood pressure over 7 years in initially normotensive children?
P
Population
117 initially normotensive Dutch children, including 39 with a large increase in systolic blood pressure and 78 matched controls with a small increase, followed for 7 years.
C
Comparator
Children with a small increase in systolic blood pressure
O
Outcome
Determinants of a large increase in systolic blood pressure over 7 yearssurrogate
A fall in blood pressure after a short follow-up period and larger weight gain may predict a high rise in blood pressure in initially normotensive children over the subsequent years.
Cite This Study
Visser et al. (1987) conducted a case-control in Normotension (n=117). Large increase in systolic blood pressure vs. Small increase in systolic blood pressure was evaluated on Determinants of rise in blood pressure (weight gain, parental history, cardiovascular reactivity, sodium excretion, tobacco consumption, initial BP fall). Children with a large rise in systolic blood pressure over 7 years experienced a larger weight gain and a greater initial fall in blood pressure at 4 weeks compared to those with a small rise.