What is the clinical evidence from this study?

Study design: Cohort. Population: Heart failure with reduced ejection fraction (HFrEF) (n=118). Intervention: Malnutrition vs. Normal nutritional status. Primary outcome: Prevalence of malnutrition.

December 31, 2025ABC Heart Failure & CardiomyopathyOpen Access

Malnutrition in Outpatients with Heart Failure: Prevalence, Associated Factors and 6-Month Impact

Q: What does this research mean for the field?

Malnutrition affects approximately 21% of outpatients with heart failure with reduced ejection fraction and is associated with older age, worse functional class, and a trend toward increased 6-month mortality. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Malnutrition affects ~21% of HFrEF outpatients and is linked to older age and worse functional class.

n=118

Why the study?

Malnutrition is common in HFrEF and may negatively affect prognosis, but its prevalence, associated clinical factors, and impact on clinical outcomes require evaluation in outpatients.

Does malnutrition impact mortality and clinical outcomes at 6 months in outpatients with HFrEF?

Population

118 outpatients with HFrEF

Comparison

Nutritional status assessed by MNA and SGA

Design

Prospective observational cohort study

Follow-up

6 months

Authors

LGLeonardo Akira Gondo LMLídia Zytynski Moura MBMarcely Gimenes Bonatto

Discussion

Member takes

Overview

Malnutrition assessment in HFrEF outpatients should not yet change practice; hypothesis-generating for prognostic role and intervention trials.

Study Design

Type

Cohort (n=118)

Multicenter

Structured PICO

Does malnutrition impact mortality and clinical outcomes at 6 months in outpatients with HFrEF?

Population

118 outpatients aged 18 years or older with heart failure with reduced ejection fraction, free of recent hospitalization, followed for 6 months.

Exposure

Malnutrition (assessed using the Mini Nutritional Assessment [MNA] and the Subjective Global Assessment [SGA])

Outcome

Mortality, hospitalizations, and emergency department visits at 6 monthshard clinical

This study evaluates the prevalence and 6-month prognostic impact of malnutrition in outpatients with HFrEF.

Limitations

Single center study
Small sample size (n=118)
Potential confounding factors such as dietary control, therapeutic adherence, or physical activity were not mentioned
Short follow-up period of 6 months
18% loss to follow-up
Multivariate analysis was exploratory and not subjected to formal model validation

Cite This Study

Gondo et al. (2025) conducted a cohort in Heart failure with reduced ejection fraction (HFrEF) (n=118). Malnutrition vs. Normal nutritional status was evaluated on Prevalence of malnutrition. Malnutrition was present in 21.2% of outpatients with heart failure with reduced ejection fraction and was associated with older age, worse functional class, and a trend toward higher 6-month mortality.

synapsesocial.com/papers/6aa9484fa35b18e46c04fade https://doi.org/10.36660/abchf.20250038i

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December 31, 2025ABC Heart Failure & CardiomyopathyOpen Access

Malnutrition in Outpatients with Heart Failure: Prevalence, Associated Factors and 6-Month Impact

View Full Paper

Ask AI

Bookmark

Key result

Malnutrition affects ~21% of HFrEF outpatients and is linked to older age and worse functional class.

n=118

Why the study?

Malnutrition is common in HFrEF and may negatively affect prognosis, but its prevalence, associated clinical factors, and impact on clinical outcomes require evaluation in outpatients.

Does malnutrition impact mortality and clinical outcomes at 6 months in outpatients with HFrEF?

Population

118 outpatients with HFrEF

Comparison

Nutritional status assessed by MNA and SGA

Design

Prospective observational cohort study

Follow-up

6 months

Authors

LGLeonardo Akira Gondo LMLídia Zytynski Moura MBMarcely Gimenes Bonatto

Discussion

Member takes

Overview

Malnutrition assessment in HFrEF outpatients should not yet change practice; hypothesis-generating for prognostic role and intervention trials.

Study Design

Type

Cohort (n=118)

Multicenter

Structured PICO

Does malnutrition impact mortality and clinical outcomes at 6 months in outpatients with HFrEF?

Population

118 outpatients aged 18 years or older with heart failure with reduced ejection fraction, free of recent hospitalization, followed for 6 months.

Exposure

Malnutrition (assessed using the Mini Nutritional Assessment [MNA] and the Subjective Global Assessment [SGA])

Outcome

Mortality, hospitalizations, and emergency department visits at 6 monthshard clinical

This study evaluates the prevalence and 6-month prognostic impact of malnutrition in outpatients with HFrEF.

Limitations

Single center study
Small sample size (n=118)
Potential confounding factors such as dietary control, therapeutic adherence, or physical activity were not mentioned
Short follow-up period of 6 months
18% loss to follow-up
Multivariate analysis was exploratory and not subjected to formal model validation

Cite This Study

synapsesocial.com/papers/6aa9484fa35b18e46c04fade https://doi.org/10.36660/abchf.20250038i

Also Consider

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