Key result
Malnutrition in ambulatory HFpEF is linked to ~94% higher 6-month risk of death or hospitalization.
Why the study?
Malnutrition may be an important geriatric condition in adults with HFpEF, but studies on its prevalence and associated clinical outcomes are limited.
Does malnutrition increase the risk of all-cause mortality and all-cause hospitalization in ambulatory patients with HFpEF?
Population
231 ambulatory HFpEF patients at two academic HFpEF programs
Comparison
Malnutrition (MNA-SF score <=11) vs normal nutritional status
Design
Two-center cohort study
Follow-up
6 months
Authors
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Malnutrition screening may aid risk stratification in ambulatory HFpEF; leaves open whether interventions improve outcomes.
Cohort (n=231)
Yes
Does malnutrition increase the risk of all-cause mortality and all-cause hospitalization in ambulatory patients with HFpEF?
Effect estimate: HR 1.94 (95% CI 1.17-3.20)
p-value: p=0.01
Malnutrition is highly prevalent in ambulatory HFpEF patients despite high rates of obesity, and is independently associated with a nearly two-fold increased risk of 6-month mortality and hospitalization.
Zainul et al. (2023) conducted a cohort in Heart failure with preserved ejection fraction (HFpEF) (n=231). Malnutrition (MNA-SF score ≤11) vs. No malnutrition was evaluated on 6-month composite of all-cause mortality and all-cause hospitalization (HR 1.94, 95% CI 1.17-3.20, p=0.01). Malnutrition in ambulatory patients with HFpEF was independently associated with a 6-month composite of all-cause mortality and hospitalization (HR 1.94; 95% CI 1.17-3.20; p=0.01).
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