Key result
Malnutrition is linked to ~56% higher adverse cardiac events in new-onset HF, but not chronic HF.
Why the study?
The differences in prevalence, severity, and prognostic impact of malnutrition between new-onset HF and worsening chronic HF patients were unclear.
Does malnutrition predict cardiac death or rehospitalization differently in older patients hospitalized with new-onset versus worsening chronic acute heart failure?
Population
210 older (≥60 years) hospitalized patients with acute HF
Comparison
Malnutrition (GNRI <92) vs no malnutrition (GNRI ≥92)
Design
Cohort study
Authors
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Malnutrition may aid risk stratification in new-onset HF; leaves open differential prognostic value and intervention targets versus worsening chronic HF.
Cohort (n=210)
Does malnutrition predict cardiac death or rehospitalization differently in older patients hospitalized with new-onset versus worsening chronic acute heart failure?
Absolute Event Rate: 50% vs 32%
p-value: p=0.007
Malnutrition is an independent predictor of adverse outcomes in older patients with new-onset acute heart failure, but not in those with worsening chronic heart failure, who have a poor prognosis regardless of nutritional status.
Matsumura et al. (2021) conducted a cohort in Acute heart failure (n=210). Malnutrition (GNRI < 92) vs. No malnutrition (GNRI ≥ 92) was evaluated on Composite endpoint including cardiac death or rehospitalization for HF (p=0.007). Malnutrition (GNRI < 92) significantly increased the risk of cardiac death or HF rehospitalization in new-onset heart failure (50% vs 32%, P=0.007), but not in worsening chronic heart failure.
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