Design
Review
Key result
A review of sarcolemmal ion transport mechanisms highlights the role of the Na+-K+ pump and coupled exchange processes in myocardial function and cardiac disease.
Authors
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Supports mechanistic hypotheses on ion transport in cardiac disease; leaves open clinical translation pending targeted trials.
This review provides a foundational overview of myocardial cation transport mechanisms and their role in cardiac homeostasis and disease.
Doohan et al. (1993) conducted a review in Cardiac disease processes (hypertrophy, cardiomyopathies, reperfusion injury). Sarcolemmal ion transport mechanisms was evaluated. A review of sarcolemmal ion transport mechanisms highlights the role of the Na+-K+ pump and coupled exchange processes in myocardial function and cardiac disease.
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