Key result
Percutaneous closure proves feasible for late leaks after initial Lariat LAA occlusion in 3 cases.
Why the study?
The occurrence of late leak after transcatheter LAA ligation and its percutaneous management had not been previously reported.
Can a percutaneous technique successfully close late leaks after Lariat transcatheter left atrial appendage ligation in patients with atrial fibrillation?
Case Report (n=3)
Can a percutaneous technique successfully close late leaks after Lariat transcatheter left atrial appendage ligation in patients with atrial fibrillation?
This report provides the first description of late leaks after Lariat LAA ligation and demonstrates a percutaneous technique for their management.
May allow percutaneous closure of late LAA leaks post-Lariat; hypothesis-generating and requires prospective validation before practice change.
Left atrial appendage (LAA) occlusion or ligation is a novel approach to stroke prevention in atrial fibrillation that may obviate the need for long-term anticoagulation. The Lariat device has received Food and Drug Administration 510K clearance for the approximation of soft tissue and has been applied to transcatheter LAA ligation using a combined trans-pericardial and transseptal approach. The occurrence of late leak after transcatheter LAA ligation and its percutaneous management has not been previously reported. Herein, we report three cases of late leak with reconstitution of the LAA after initially successful Lariat closure, and present a simple percutaneous technique for leak closure.
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Mosley et al. (2013) conducted a case report in Atrial fibrillation at high risk for stroke with late leak after Lariat transcatheter LAA ligation (n=3). Percutaneous management of late leak was evaluated on Leak closure. Percutaneous management is a feasible technique for closing late leaks with reconstitution of the left atrial appendage after initially successful Lariat closure in three reported cases.
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