Key result
Rapidly progressive mediastinal undifferentiated pleomorphic sarcoma infiltrates large blood vessels, causing death within 33 days.
Why the study?
Primary mediastinal sarcomas are very rare, but clinicians should be aware of them because some cases may progress rapidly.
Case Report (n=1)
Primary mediastinal sarcomas are very rare and can progress rapidly, requiring clinical awareness.
May prompt sarcoma consideration in rapidly progressive mediastinal masses; leaves open optimal diagnostic and therapeutic strategies.
A 77-year-old woman with heart failure was admitted to our hospital. Computed tomography (CT) of the chest revealed an anterior mediastinal tumor. CT-guided biopsy revealed a malignant nonepithelial tumor of unknown origin. She was not treated with chemotherapy or radiotherapy because of her poor clinical condition. She died 33 days after admission. Following autopsy, we confirmed that the mediastinal tumor had infiltrated the large blood vessels. After final histological examination, undifferentiated pleomorphic sarcoma was diagnosed. Primary mediastinal sarcomas are very rare; clinicians should be aware of their possibility because some cases may progress rapidly as evidenced in this case.
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Sato et al. (2020) conducted a case report in Undifferentiated pleomorphic sarcoma in the anterior mediastinum (n=1). A 77-year-old woman with an anterior mediastinal tumor died 33 days after admission, with autopsy confirming a rapidly progressive undifferentiated pleomorphic sarcoma infiltrating large blood vessels.
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