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The poor solubility in water of vitamin D results into low bioavailability, which significantly reduces its efficacy to combat the associated disorders. Encapsulated nanoparticles (ENs) seem an indispensable tool to formulate effective delivery systems, which could enhance its bioavailability as a function of various players: improving stability of lipophilic compound in the target foods as well as the gastrointestinal tract (GIT), enhancing its solubility in intestinal juice, facilitating its absorption by GIT, and reducing first-pass metabolism loss in the gut and liver. This review is the depictions the mode of actions of various food-grade ENs in enhancing the bioavailability of vitamin D.
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Maurya et al. (2017) studied this question.
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