Key result
White adipose tissue expansion capacity shapes metabolic health in obesity via emerging isotopic labeling methods.
Why the study?
The role of adipogenesis in the transition from impaired subcutaneous white adipose tissue expansion to impaired metabolic health remains debated.
Design
Mini-review
Authors
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Leaves open adipogenesis contribution to metabolic impairment in obesity; hypothesis-generating, requiring prospective trials before clinical consideration.
This review highlights emerging concepts on white adipose tissue expansion and turnover, and their significance in obesity and metabolic health.
Ursula White (2023) conducted a review in Obesity and metabolic health. White adipose tissue expansion capacity is a significant determinant of metabolic health in obesity, with emerging isotopic labeling methods providing new insights into in vivo lipid and cell kinetics.
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