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October 6, 2020Biological Chemistry

Expansion and inflammation of white adipose tissue - focusing on adipocyte progenitors

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Key result

Adipocyte progenitors play a key role in obesity-associated white adipose tissue expansion, inflammation, and fibrosis.

Why the study?

The expansion and inflammation of white adipose tissue are causally linked to metabolic and cardiovascular diseases, but the primary event triggering this inflammatory expansion remains unclear.

Design

Review

Authors

WLWenjing LiuDLDahui LiHCHandi Cao

Discussion

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Member takes

Overview

May inform obesity-related cardiovascular risk mechanisms; leaves open targeted progenitor therapies.

PICO

P
Population
Obesity-associated white adipose tissue expansion, inflammation, and fibrosis
E
Exposure / Comparator
Adipocyte progenitors (APS)

This review highlights the role of adipocyte progenitors in obesity-associated white adipose tissue expansion, inflammation, and fibrosis, which are linked to metabolic and cardiovascular diseases.

Cite This Study

Liu et al. (2020) conducted a review in Obesity-associated white adipose tissue expansion, inflammation, and fibrosis. Adipocyte progenitors (APS) was evaluated. Adipocyte progenitors play a key role in obesity-associated white adipose tissue expansion, inflammation, and fibrosis.

synapsesocial.com/papers/6a897208502e90db67719f3ahttps://doi.org/10.1515/hsz-2019-0451
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adipose tissue expansion in obesity, health, and disease2023 · 97 citations
  2. 2Fate of Adipose Progenitor Cells in Obesity-Related Chronic Inflammation2020 · 34 citations
  3. 3Activatin' Human Adipose Progenitors in Obesity2010 · 26 citations
  4. 4Current Progress in Adipose Tissue Biology: Implications in Obesity and Its Comorbidities2020 · 4 citations
  5. 5Origin of White and Brown Adipose Cells From Vascular Endothelium: A Dissertation2012