Key result
Surgery plus prednisone achieves rapid nephrotic syndrome remission in a Kimura disease case.
Why the study?
Kimura disease is an uncommon chronic inflammatory disorder that can be difficult to diagnose and may be misdiagnosed, especially when accompanied by nephrotic syndrome.
Case Report (n=1)
Surgical excision and systemic prednisone therapy successfully treated an atypical presentation of Kimura disease with nephrotic syndrome in a middle-aged man.
Surgical excision plus prednisone may induce remission in Kimura disease with nephrotic syndrome; leaves open efficacy in larger cohorts.
Kimura disease (KD) is an uncommon chronic inflammatory disorder of unknown etiology, occurs mainly in Asian young males, presenting as subcutaneous growing masses, with a predilection for head and neck, with or without satellite lymphadenopathy. Herein, we report a case of an atypical manifestation of KD accompanied with NS in a middle-aged man, though the patient was clinically misdiagnosed previously. The diagnosis of KD can be difficult and misleading, so we must explore the main points of KD so as to prevent misdiagnosis.
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Gong et al. (2015) conducted a case report in Kimura disease accompanied with Nephrotic syndrome (n=1). Surgical excision and oral prednisone was evaluated on Clinical response (remission of nephrotic syndrome and normalization of laboratory values). Surgical excision followed by oral prednisone treatment resulted in rapid remission of nephrotic syndrome, normalization of eosinophil counts and IgE levels, and no disease recurrence after 7 months in a 45-year-old man with Kimura disease.
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