Key result
Steroid, endoxan, and MMF successfully treat atypical Kimura disease with secondary nephrotic syndrome.
Why the study?
Kimura disease is a rare chronic inflammatory disorder with unknown etiology that can present atypically and be difficult to diagnose, leading to avoidable procedures.
Case Report (n=1)
Kimura disease can present atypically in middle-aged Caucasian men with nephrotic syndrome and can be successfully managed with steroids, endoxan, and MMF.
May support immunosuppression for atypical Kimura disease with nephrotic syndrome; hypothesis-generating and requires prospective confirmation.
Kimura disease (KD) is a chronic inflammatory disorder with angiolymphatic proliferation, usually affecting young men of Asian race but is rare in other races. The etiology of KD is still unknown. It is often accompanied by nephrotic syndrome. Herein, we present an atypical manifestation of Kimura disease occurring in a Caucasian man with steroid-responsive early membranous glomerulonephritis. Kimura disease can present atypically in a middle-aged Caucasian man with secondary steroid-responsive nephrotic syndrome. Steroid, endoxan, and MMF can be used safely and successfully in such situation. The diagnosis of KD can be difficult and misleading, and patients with this disease are often evaluated using avoidable procedures by just not being aware of KD.
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Fouda et al. (2010) conducted a case report in Kimura disease with steroid-responsive early membranous glomerulonephritis (n=1). Steroid, endoxan, and MMF was evaluated on Safety and success of treatment. Steroid, endoxan, and MMF were used safely and successfully to treat an atypical presentation of Kimura disease with secondary steroid-responsive nephrotic syndrome in a middle-aged Caucasian man.
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