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September 1, 2026Journal of Clinical HypertensionOpen Access

Predictive Value of D‐Dimer to Albumin Ratio for Outcome in Acute Type A Aortic Dissection Patients

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Authors

ALAijie LinFujian Medical UniversityYPYanchun PengFujian Medical UniversityJSJiayi ShaoFujian Medical University

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Overview

Retrospective study reveals elevated D-dimer to albumin ratio predicts 30-day postoperative mortality in acute type A aortic dissection, indicating its utility for surgical risk stratification.

Key Points

  • To evaluate the association between the preoperative D-dimer to albumin ratio (DAR) and 30-day postoperative adverse outcomes in acute type A aortic dissection.
  • Retrospective cross-sectional study of N = 619 patients with acute type A aortic dissection undergoing surgery at Fujian Medical University Union Hospital between July 2013 and December 2021.
  • Assessed the association between preoperative DAR and outcomes using multivariable logistic regression and evaluated discrimination via receiver operating characteristic (ROC) curves.
  • Overall 30-day postoperative mortality was 17.12% (106/619), with the highest incidence of mortality and adverse cardio- and cerebrovascular events observed in the highest DAR category.
  • Multivariate regression confirmed DAR as an independent predictor of 30-day mortality (OR: 3.604, 95% CI: 1.495–8.685, p = 0.004).
  • DAR exhibited good predictive ability for 30-day postoperative mortality, achieving an area under the curve of 0.710 (95% CI: 0.656–0.764, P < 0.001).

Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/6aab48e93d19c5e761856f3bhttps://doi.org/10.1111/jch.70339
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